10.19261/cjm.2016.11(1).05
Bulhac, I.I.
Institutul de Chimie al AŞM, Moldova, Republica
Ciloci (Deseatnic), A.A.
Institutul de Microbiologie şi Biotehnologie al AŞM, Moldova, Republica
Bouroş, P.N.
Institutul de Fizică Aplicată al AŞM, Moldova, Republica
Tiurina, J.P.
Institutul de Microbiologie şi Biotehnologie al AŞM, Moldova, Republica
Bologa, O.A.
Institutul de Chimie al AŞM, Moldova, Republica
Bivol, C.M.
Institutul de Microbiologie şi Biotehnologie al AŞM, Moldova, Republica
Clapco, S.F.
Institutul de Microbiologie şi Biotehnologie al AŞM, Moldova, Republica
Verejan, A.
Institutul de Chimie al AŞM, Moldova, Republica
Labliuc, S.V.
Institutul de Microbiologie şi Biotehnologie al AŞM, Moldova, Republica
Danilescu, O.S.
Institutul de Chimie al AŞM, Moldova, Republica
Structure and some biological properties of Fe(III) complexes with nitrogen-containing ligands
Instrumentul Bibliometric National
2016
1857-1727
iron complexes
nitrogen-containing ligands
structure
biological properties
547.915:577.1
2016-06-22
Journal article
Four coordination compounds of iron(III) with ligands based on hydrazine and sulfadiazine: [Fe(dig)]Cl3·2H2O (I) (dig-semicarbazide diacetic acid dihydrazide), [Fe(HL)SO4] (II) (НL - sulfadiazine), [Fe(H2L1)(H2O)2](NO3)3·5H2O (III) (H2L1-2,6-diacetylpyridine bis(nicotinoylhydrazone) and [Fe(H2L2)(H2O)2](NO3)3·1.5H2O (IV) (H2L2 - 2,6-diacetylpyridine bis(isonicotinoylhydrazone) were synthesized. The spectroscopic and structure characterisation, as well as their biological properties, are presented. All tested coordination compounds, caused an inhibitory effect on the biosynthesis of hydrolases of the producer Aspergillus niger CNMN FD-10. The effect increased with the raise of the concentration from 5 mg/L to 15 mg/L. The complexes largely inhibited cellobiohydrolase and less- β-glucosidase. The inhibitory effect of the coordination compounds was quite similar in the case of endoglucanase and xylanase. Compound I, containing both chloride ions and dig, demonstrated a stronger inhibitory effect, while compound III, containing NO3 - ions, showed the weakest inhibitory action.
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