10.19261/cjm.2016.11(1).05 Bulhac, I.I. Institutul de Chimie al AŞM, Moldova, Republica Ciloci (Deseatnic), A.A. Institutul de Microbiologie şi Biotehnologie al AŞM, Moldova, Republica Bouroş, P.N. Institutul de Fizică Aplicată al AŞM, Moldova, Republica Tiurina, J.P. Institutul de Microbiologie şi Biotehnologie al AŞM, Moldova, Republica Bologa, O.A. Institutul de Chimie al AŞM, Moldova, Republica Bivol, C.M. Institutul de Microbiologie şi Biotehnologie al AŞM, Moldova, Republica Clapco, S.F. Institutul de Microbiologie şi Biotehnologie al AŞM, Moldova, Republica Verejan, A. Institutul de Chimie al AŞM, Moldova, Republica Labliuc, S.V. Institutul de Microbiologie şi Biotehnologie al AŞM, Moldova, Republica Danilescu, O.S. Institutul de Chimie al AŞM, Moldova, Republica Instrumentul Bibliometric National 2016 1857-1727 iron complexes nitrogen-containing ligands structure biological properties 547.915:577.1 2016-06-22 Journal article Four coordination compounds of iron(III) with ligands based on hydrazine and sulfadiazine: [Fe(dig)]Cl3·2H2O (I) (dig-semicarbazide diacetic acid dihydrazide), [Fe(HL)SO4] (II) (НL - sulfadiazine), [Fe(H2L1)(H2O)2](NO3)3·5H2O (III) (H2L1-2,6-diacetylpyridine bis(nicotinoylhydrazone) and [Fe(H2L2)(H2O)2](NO3)3·1.5H2O (IV) (H2L2 - 2,6-diacetylpyridine bis(isonicotinoylhydrazone) were synthesized. The spectroscopic and structure characterisation, as well as their biological properties, are presented. All tested coordination compounds, caused an inhibitory effect on the biosynthesis of hydrolases of the producer Aspergillus niger CNMN FD-10. The effect increased with the raise of the concentration from 5 mg/L to 15 mg/L. The complexes largely inhibited cellobiohydrolase and less- β-glucosidase. The inhibitory effect of the coordination compounds was quite similar in the case of endoglucanase and xylanase. Compound I, containing both chloride ions and dig, demonstrated a stronger inhibitory effect, while compound III, containing NO3 - ions, showed the weakest inhibitory action. application/pdf