Author(s):
Lauro Figueroa, Alejandra Garcimarero, Rolando Garcia, Francisco Diaz, Marcela Rosas, Virginia Mateu, Maria Lopez, Lenin Hau, Tomas Lopez, Abelardo Camacho, Yaritza Borges
Field: Organic chemistry
Type: Research paper
Issue: 2020 Volume 15, no.1
Pages: 75-85
Abstract (PDF)
Graphical Abstract: This study describes the preparation of two bicyclo[3.3.3]nonane-steroid derivatives from either estradiol or estrone using some reactions such as etherification, addition, nucleophilic substitution and cyclization. The chemical structure was evaluated through NMR spectroscopic analysis. The results showed higher yield for
11 compared with
12. It is noteworthy that the reagents used in this investigation are not expensive and do not require special conditions for handling.
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