Chemistry Journal of Moldova

DERIVATIZATION TECHNIQUES BASED ON CHARGE TRANSFER REACTIONS FOR SPECTROPHOTOMETRIC DETERMINATION OF JOSAMYCIN IN VARIOUS DOSAGE FORMS

Author(s):

Abdelghani Mahmoudi and Ann Van Schepdael


Field: Analytical chemistry
Type: Research paper
Issue: 2024 Volume 19, no.1
Pages: 37-46
Keywords:

spectrophotometric analysis, josamycin, 1,4-naphthoquinone-4-sulphonate, menadione.


Full Text (PDF): Download
 

https://doi.org/10.19261/cjm.2024.1165

Abstract (PDF)
Graphical Abstract: The developed spectrophotometric methods were based on charge transfer reactions of naphthoquinones with Josamycin. Methods validity was tested and the results were in accordance with ICH guidelines. Procedures showed successful adaptability for an easy analysis of this macrolide in various dosage forms and can be used for quality control purposes.


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