Chemistry Journal of Moldova

OPTIMIZATION OF ULTRASOUND-ASSISTED EXTRACTION OF ANTIOXIDANT PHENOLICS FROM ALGERIAN TRIFOLIUM TOMENTOSUM L. USING RESPONSE SURFACE METHODOLOGY

Author(s):

Radia Hannache, Radia Ayad, Nassima Boutaoui, Hayat Bourekoua, Mostefa Lefahal, El Hani Makhloufi, Nabila Souilah, Salah Akkal, Kamel Medjroubi


Field: Natural product chemistry and synthesis
Type: Research paper
Issue: 2024 Volume 19, no.2
Pages: 52-62
Keywords:

Trifolium tomentosum L., antioxidant phenolics, green process, ultrasonic, response surface methodology.


Full Text (PDF): Download
 
https://doi.org/10.19261/cjm.2024.1221

Abstract (PDF)
Graphycal Abstract: The current study aims to maximize the recovery of antioxidant phenolics from Algerian Trifolium tomentosum L. using an innovative green process: ultrasonic assisted extraction (UAE). Using response surface methodology (RSM), the optimal UAE parameters for maximum responses (total phenolic content, total flavonoid content, and total antioxidant capacity) were 70% ethanol concentration, 30.45 minutes of extraction time, and 75°C extraction temperature.




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