DOI: dx.doi.org/10.19261/cjm.2013.08(1).02 Graphical Abstract: This paper represents an analysis of the research concerning the use of fertilizers and nutrients balance in the soils of the Republic of Moldova. The nature and effectiveness of fertilizers, their influence on the agrochemical properties of soils, the protection of the environment from the pollution by nutrients in addition to the regulatory normatives of our country developed in order to determine the necessary in fertilizers for obtaining the expected crops have been as well discussed.