Chemistry Journal of Moldova

SYNTHESIS, OPTIMIZATION, CHARACTERIZATION AND ANTIMICROBIAL STUDIES OF Cu(II) AND Co(III) COMPLEXES OF BIS(2,2/-METHYLYLIDENEPHENOL)DIAMINOETHANE

Author(s):

Felix Sunday Nworie, Frank Ikenna Nwabue


Field: Inorganic and coordination chemistry
Type: Research paper
Issue: 2017 Volume 12, no.2
Pages: 41-49
Keywords:

H2BMPDE-complex, modelling, physicochemical study, antimicrobial bio-efficiency.


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Abstract (PDF)
Graphical Abstract: A new synthetic extractive protocol for the synthesis of Cu(II) and Co(III) complexes of bis(2,2/-methylylidenephenol)diaminoethane (H2BMPDE) in a single simple step was performed. The obtained data indicated the formation of complexes with 1:1 molar ratio of metal:ligand, of distorted square planar and distorted octahedral geometries. In vitro antibacterial screening revealed that the complexes were active against clinically important gram-negative bacteria (Escherichia coli, pseudomonas, and gram-positive bacterium (Staphylococcus aureus). The synthesis of the complexes was optimized to make it more suitable and efficient for industrial scale production.


 
 


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