Chemistry Journal of Moldova

CHEMICAL COMPOSITION AND BIOLOGICAL EVALUATION OF TRADITIONAL ALGERIAN PLANTS MELISSA OFFICINALIS L. AND URTICA DIOICA L.

Author(s):

Dahia Meridja, Kamel Belhamel, Mohamed Harrat, Chiraz Belhamel, Mohamed Yousfi


Field: Natural product chemistry and synthesis
Type: Research paper
Pages:
Keywords:

Melissa officinalis L., Urtica dioica L., LC-MS/MS, antioxidant activity, anti-lithiatic activity.


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https://doi.org/10.19261/cjm.2025.1328
 
Abstract (PDF)
Graphycal Abstract: Melissa officinalis L. and Urtica dioica L. were evaluated for their phytochemical composition and antioxidant and anti-lithiatic activities. LC-MS/MS analysis showed that M. officinalis contained a more diverse profile, especially flavonoids and phenolic acids enriched in the ethyl acetate fraction, while U. dioica demonstrated a simpler composition dominated by myricetin, riboflavin, sinapic acid, catechin, and β-carotene in its aqueous fraction. M. officinalis ethyl acetate extract showed the strongest antioxidant capacity in DPPH, ABTS, and FRAP assays. Its aqueous extract also exhibited notable anti-lithiatic activity, inhibiting calcium oxalate crystal formation by 87.12% at 2 mg/mL.

 


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