Chemistry Journal of Moldova

SYNTHESIS OF CHITOSAN GRAFTED WITH AMINOMETHYL ZINC PHTHALOCYANINE FOR PHOTODYNAMIC THERAPY

Author(s):

Stefan Robu, Tamara Potlog, Ion Bulimestru, Ion Lungu, Olga Sadohina, Alexandrina Druta, Petru Bulmaga, Iacob Gutu


Field: Organic chemistry
Type: Research paper
Pages:
Keywords:

ZnPc derivative, chitosan, grafting reaction, UV-Vis spectroscopy, FTIR spectroscopy.


Full Text (PDF): Download
 
https://doi.org/10.19261/cjm.2025.1217
 
Abstract (PDF)
Graphycal Abstract: This study presents the synthesis of a novel polymer analogue derived from aminomethyl zinc phthalocyanine (AmPcZn) and chitosan (CH). The polymer was produced by grafting AmPcZn onto chitosan using ethyl chloroformate as a coupling agent. The resulting CH–AmPcZn polymers, containing 10%, 20%, 30%, and 60% AmPcZn, were characterized using FTIR and UV-Vis spectroscopy. The UV-Vis analysis showed that absorbance increased with higher concentrations of AmPcZn in the CH–AmPcZn solutions.


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