Natural product chemistry and synthesis

STUDY ON EXTRACTION PROCESS OF SUNFLOWER (HELIANTHUS ANNUUS L.) DRY WASTES USING DIFFERENT SOLVENTS

Author(s):

Olga Morarescu, Marina Grinco, Ion Dragalin, Veaceslav Kulciţki, Nicon Ungur

Field: Natural product chemistry and synthesis
Type: Research paper
Issue: 2013 Volume 8, no.2
Pages: 90-93

Keywords: ent-kaur-16-en-19-oic acid, 15α-angeloyl-ent-kaur-16-en-19-oic acid, ent-trachiloban-19-oic acid, diterpene, extraction
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Abstract (PDF)

DOI: dx.doi.org/10.19261/cjm.2013.08(2).11

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MOLECULAR REARRANGEMENTS OF HIGHLY FUNCTIONALIZED TERPENES. AN UNIQUE REACTIVITY OF BICYCLIC FRAMEWORK AND POLIENIC CHAIN INHIBITION UNDER SUPERACIDIC TREATMENT

Author(s):

Marina Grinco, Veaceslav Kulciţki, Pavel F. Vlad, Alic Barba, Elena Gorincioi, Nicon Ungur

Field: Natural product chemistry and synthesis
Type: Research paper
Issue: 2013 Volume 8, no.2
Pages: 94-100

Keywords: triterpenes, synthesis, superacid, isomerization
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Abstract (PDF)

DOI: dx.doi.org/10.19261/cjm.2013.08(2).12

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(-)-SCLAREOL CONVERSION IN RITTER'S REACTION CONDITIONS

Author(s):

S. Kovalskaya, N. Kozlov, A. Aricu, V. Kulcitki, N. Ungur

Field: Natural product chemistry and synthesis
Type: Short communication
Issue: 2012 Volume 7, no.2
Pages: 147-148

Keywords: diterpenoids, Ritter’s reaction, diamide, sclareol.
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Abstract (JPEG)

DOI: dx.doi.org/10.19261/cjm.2012.07(2).01

Graphical Abstract: The main products of sclareol (1) Ritter’s reaction in mild conditions are (8R,13R)-Labd-14(15)-en-8,13-diacetamide (2) (8R,13S)-Labd-14(15)-en-8,13-diacetamide (3) stereoisomeric on C13 atom and having unrearranged native diol skeleton. We present in the current communication the results of sclareol converting (1) into nitrogen-containing labdanes
in the Ritter’s reaction conditions.

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HYALURONIC ACID: OBTAINING, PROPERTIES AND APPLICATION

Author(s):

L. Zadorojnai, A. Zadorojnai

Field: Natural product chemistry and synthesis
Type: Review
Issue: 2012 Volume 7, no.2
Pages: 57-66

Keywords: hyaluronic acid, obtaining methods, natural sources.
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Abstract (JPEG)

DOI: dx.doi.org/10.19261/cjm.2012.07(2).13

Graphical Abstract: Properties and methods for obtaining hyaluronic acid and its derivatives from raw material of animal origin are reviewed.
The importance and practical application of hyaluronic acid in various fields are discussed. This article is an extended abstract of a communication presented at the Conference Ecological Chemistry 2012.

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BIOMIMETIC STRATEGIES IN ORGANIC SYNTHESIS. TERPENES

Author(s):

V. Kulcitki

Field: Natural product chemistry and synthesis
Type: Review
Issue: 2012 Volume 7, no.2
Pages: 46-56

Keywords: terpenoids, biomimetic synthesis, cyclisation, rearrangement, oligomerisation, functionalisation.
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Abstract (JPEG)

DOI: dx.doi.org/10.19261/cjm.2012.07(2).14

Graphical Abstract: The current paper represents an outline of the selected contributions to the biomimetic procedures and approaches for the synthesis of terpenes with complex structure and diverse functionalisation pattern. These include homologation strategies, cyclisations, rearrangements, as well as biomimetic remote functionalisations.

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STEROIDAL GLYCOSIDES FROM VERONICA CHAMAEDRYS L. PLANTS. THE STRUCTURES OF CHAMAEDROSIDES A, B, C AND E

Author(s):

Alexandra Marchenko, Pavel Kintia, Bożena Wyrzykiewicz

Field: Natural product chemistry and synthesis
Type: Research paper
Issue: 2010 Volume 5, no.2
Pages: 54-58

Keywords: steroidal glycoside, NMR analysis, Veronica chamaedrys L.
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Abstract (JPEG)

DOI: dx.doi.org/10.19261/cjm.2010.05(2).07

Graphical Abstract: The paper reports on the structural elucidation of the four steroidal glycosides, where two are new, isolated from Veronica chamaedrys L. plants for the first time on the basis of extensive spectral analysis, including 2D NMR spectral data and chemical evidences.

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OBSERVATIONS ON THE ANTIOXIDANT ACTIVITY OF NOVEL DIHYDROXYFUMARIC ACID DERIVATIVES

Author(s):

N. Secara, Gh. Duca, L. Vlad, F. Macaev

Field: Natural product chemistry and synthesis
Type: Research paper
Issue: 2010 Volume 5, no.2
Pages: 59-67

Keywords: dihydroxyfumaric acid derivatives, DPPH test, antioxidant activity.
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Abstract (JPEG)

DOI: dx.doi.org/10.19261/cjm.2010.05(2).08

Graphical Abstract: The paper describes the syntheses of new derivatives of dihydroxyfumaric acid and investigations of their antioxidant activities using the DPPH method.

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C15 FUNCTIONALIZED DERIVATIVES OF ent-KAUR-16-EN-19-OIC ACID: ISOLATION FROM THE SUNFLOWER HELIANTHUS ANNUUS L. AND SYNTHESIS

Author(s):

Marina Grinco, Olga Chetraru, Veaceslav Kulciţki, Alic Barba, Alexandr Boico, Pavel F. Vlad and Nicon Ungur

Field: Natural product chemistry and synthesis
Type: Research paper
Issue: 2010 Volume 5, no.1
Pages: 106-108

Keywords: diterpene, isolation, synthesis, 15α-angeloyl-ent-kaur-16-en-19-oic acid, 15α-hydroxy-ent-kaur-19-oic acid, 15-oxo-ent-kaur-16-en-19-oic acid.
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Abstract (JPEG)

DOI: dx.doi.org/10.19261/cjm.2010.05(1).11

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SYNTHESYS OF A FUNCTIONALIZED TETRAHYDROFURAN FRAGMENT THROUGH BROMINATION-CYCLIZATION OF A CONJUGATED DIENE

Author(s):

Veaceslav Kulciţki, Marina Cara, Andrea Bourdelais, Tomas Schuster and Daniel Baden

Field: Natural product chemistry and synthesis
Type: Short communication
Issue: 2010 Volume 5, no.1
Pages: 118-120

Keywords: Terpenoids, furans, NBS, conjugate addition.
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Abstract (JPEG)

DOI: dx.doi.org/10.19261/cjm.2010.05(1).13

Graphical Abstract: Conjugate 1,4-addition of N-bromosuccinimide (NBS) to a diene system, possessing a suitable oxygen functionality, leads to functionalized tetrahydrofuran derivatives, which can be further derivatized into different synthetic targets.

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A RETRO-BIOMIMETIC ONE-STEP SYNTHESIS OF NATURAL ATISANIC AND BEYERANIC DITERPENOIDS

Author(s):

Olga Chetraru, Marina Grinco, Veaceslav Kulciţki, Pavel F. Vlad and Nicon Ungur

Field: Natural product chemistry and synthesis
Type: Short communication
Issue: 2010 Volume 5, no.1
Pages: 121-123

Keywords: Terpenoids, biomimetic synthesis, kaurane, atisane, beyerane.
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Abstract (JPEG)

DOI: dx.doi.org/10.19261/cjm.2010.05(1).14

Graphical Abstract: The direct, one step conversion of ent-kaurenoic acid 3 into atisanic and beyeranic acids 1 and 2 was performed under the action of fluorosulfonic acid.

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