Chemistry Journal of Moldova

DOI: dx.doi.org/10.19261/cjm.2012.07(2).01

Graphical Abstract: The main products of sclareol (1) Ritter’s reaction in mild conditions are (8R,13R)-Labd-14(15)-en-8,13-diacetamide (2) (8R,13S)-Labd-14(15)-en-8,13-diacetamide (3) stereoisomeric on C13 atom and having unrearranged native diol skeleton. We present in the current communication the results of sclareol converting (1) into nitrogen-containing labdanes
in the Ritter’s reaction conditions.


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DOI: dx.doi.org/10.19261/cjm.2012.07(2).13

Graphical Abstract: Properties and methods for obtaining hyaluronic acid and its derivatives from raw material of animal origin are reviewed.
The importance and practical application of hyaluronic acid in various fields are discussed. This article is an extended abstract of a communication presented at the Conference Ecological Chemistry 2012.


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DOI: dx.doi.org/10.19261/cjm.2012.07(2).14

Graphical Abstract: The current paper represents an outline of the selected contributions to the biomimetic procedures and approaches for the synthesis of terpenes with complex structure and diverse functionalisation pattern. These include homologation strategies, cyclisations, rearrangements, as well as biomimetic remote functionalisations.

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DOI: dx.doi.org/10.19261/cjm.2010.05(1).13

Graphical Abstract: Conjugate 1,4-addition of N-bromosuccinimide (NBS) to a diene system, possessing a suitable oxygen functionality, leads to functionalized  tetrahydrofuran derivatives, which can be further derivatized into different synthetic targets.


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DOI: dx.doi.org/10.19261/cjm.2011.06(2).01

Moldovan chemists hosted the Italian partners in Chisinau and organized in premiere for the last 20 years an international seminar devoted to the chemistry of natural products. The seminar’s motto: New Frontiers in the Chemistry of Natural Products has addressed numerous students and researchers acting in the fields of chemistry, biology, pharmacy, genetics, biophysics as well as specialists from the R&D sector of companies with chemico-pharmaceutical profile. Following multiple solicitations coming from seminar audience, made us provide in the current issue of the  “Chemistry Journal of Moldova. General, Industrial and Ecological Chemistry” a condensed abstract of the seminar presentations. We do really hope that our joint event will give further impetus to our collaboration and will also motivate other researchers from Moldova to develop partnerships with European colleagues.


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DOI: dx.doi.org/10.19261/cjm.2011.06(2).02

Graphical Abstract: The topic of the seminar held in the Institute of Chemistry, Academy of Sciences of Moldova on 30th September in the frame of the joint Moldo-Italian seminar “New frontiers in natural product chemistry”, concerned the use of NMR techniques in the elucidation of natural products. Step by step, two marine compounds (Fulvyne C and Tritoniopsin A) belonging to different chemical classes have been analyzed, by using suitable NMR experiments. This powerful technique allowed the elucidation of compounds as fulvynes, long chain polyacetylenes with the same functional groups but differently located in the chain, as well as tritoniopsins, cyclic diterpenes with a new skeleton, providing further information on their relative and absolute stereochemistry.


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